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Furthermore, chronic systemic inflammation induces a state of anabolic resistance within the muscle tissue

Stosiek, C., Garaschuk, O., Holthoff, K

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elegans to lamprey

The receptor enhancement produced by both ascorbic acid and opioid drugs is characterized by increased receptor activity in the presence of agonists at any submaximal dose, increased duration of activity at any given agonist dose, as well as reversal of tachyphylaxis and/or fade in tissues regulated by the receptor [49,50,51,52,58,59,60,61,62,63,69]